Quote Originally Posted by fastupslowdown View Post
I will get the vaccine once my doctor and his hospital network signs off. But i'm interested in the differences between the Pfizer and Moderna vaccine. I understand they have similar efficacy rates yet I find it peculiar they are viewed equally when the Moderna has less expensive and stringent storage requirements and the required dosage less 30mg vs 100mg. Seems like Moderna chose a similar path but has far better technology involved -Mike G
They think the temperature difference is due to the differences in the delivery molecule (solid lipid nanoparticle) used to coat the mRNA strand. Moderna's is coating seems to be most robust and doesn't need to be as cold as pfizers. ( MRNA-1273 from Moderna, and BNT162b2 from BioNTech/Pfizer)

You can think of the lipid like the coating on your M&M chocolate. The chocolate inside is the mRNA, the coating is the lipid. You want it to melt in your mouth not in your hand. :)